hctrial                 hctrial: A package for designing phase 2
                        clinical trials adjusting for heterogeneous
                        populations.
hist_end                Adjust a design based on historical controls at
                        the end of the study using the covariate data
                        of the patients accrued in stage 2.
hist_interim            Adjust a design based on historical controls at
                        interim using the covariate data of the
                        patients accrued in stage 1.
hist_start              Initializes a design based on historical
                        controls before the start of the study.
strat_end               Adjust a subspace stratified design at the end
                        of the study.
strat_interim           Adjust a subspace stratified design at interim.
strat_start             Initializes a subspace stratified design before
                        the start of the study.
